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Supporting Research for the Orgasm Shot®


Runels CE, Melnick H, DeBourbon E., A Pilot Study of the Effect of Localized Injections of Autologous Platelet Rich Plasma (PRP) for the Treatment of Female Sexual Dysfunction. J Women’s Health Care 2014, 3:4
--->>>Click here to read. The introduction explains the science of the O-Shot®
 
Posey K, Runels C, In Office Surgery and Use of Platelet Rich Plasma for Treatment of Vulvar Lichen Sclerosus to Alleviate Painful Sexual Intercourse, Journal of Lower Genital Tract Disease. 2017 Vol 21, #45. S14
 
Matz, EL: Safety and feasibility of platelet rich fibrin matrix injections for treatment of common urologic conditions Demonstrates O-Shot® methodology could be widely effective for stress incontinence in Women
 
Neto JB, O-Shot®: O-Shot: Platelet Rich Plasma in Intimate Female Treatment - oshot-platelets-rich-plasma-in-intimate-female-treatment-2167-0420-1000395
 
Goldstein AT, King M, Runels C, Gloth M, Pfau R, Intradermal injection of autologous platelet-rich plasma for the treatment of vulvar lichen sclerosus. Journal of the American Academy of Dermatology, 2017, 76(1), 158-160 (click to read)
 
Fabria, B: Use of Platelet-rich Plasma for Vulvovaginal Autoimmune Conditions Like Lichen Sclerosus. Shows that O-Shot® techniques can work for lichen sclerosus
 
Oakley Sh, et al, Clitoral size and location in relation to sexual function using pelvic MRI J Sex Med. 2014 Apr:11 (4):1013-1022
 
Michelle King MSc, Hillary Tolson, Charles Runels MD, Meghan Gloth MD, Richard Pfau MD, Andrew T Goldstein MD (lead investigator). Autologous Platelet Rich Plasma (PRP) Intradermal Injections for the Treatment of Vulvar Lichen Sclerosus
Hom DB, Linzie BM, Huang TC. The healing effects of autologous platelet gel on acute human skin wounds. Arch Facial Plast Surg. 2007;9(3):174-183.Sclafani AP, Romo TR III, Ukrainsky G, et al. Modulation of wound response and soft tissue ingrowth in synthetic and allogeneic implants with platelet concentrate. Arch Facial Plast Surg. 2005;7(3):163-169.
 
O'Connell SM, Impeduglia T, Hessler K, Wang XJ, Carroll RJ, Dardik H. Autologous platelet-rich fibrin matrix as cell therapy in the healing of chronic lowerextremity ulcers. Wound Repair Regen. 2008;16(6):749-756.
 
Cervelli, Valerio MD; Lucarini, Lucilla MD.Use of Platelet-Rich Plasma and Hyaluronic Acid in the Loss of Substance with Bone Exposure. Advances in Skin & Wound Care: April 2011 - Volume 24 - Issue 4 - pp 176-181 [This one shows using the same techniques used in the Vampire Facelift (R) procedure to grow new skin WHERE THERE IS NO SKIN]
 
Redaelli, AlessioFace and neck revitalization with Platelet-rich plasma (PRP): clinical-outcome in a series of 23 consecutively treated patients. Journal of Drugs in Dermatology - May 1, 2010
 
Azzena B, Mazzoleni F, Abatangelo G, Zavan B, Vindigni V. Autologous plateletrich [Using Regen prepared platelet-derived growth factors (a single-spin centrifuge) to rejuvenate the face & neck] plasma as an adipocyte in vivo delivery system: case report. Aesthetic Plast Surg. 2008;32(1):155-161.
 
Cervelli V, Gentile P, Grimaldi M. Regenerative surgery: use of fat grafting combined10with platelet-rich plasma for chronic lower-extremity ulcers. Aesthetic Plast Surg. 2009;33(3):340-345.
 
Cervelli V, Palla L, Pascali M, De Angelis B, Curcio BC, Gentile P. Autologous
 
platelet-rich plasma mixed with purified fat graft in aesthetic plastic surgery. Aesthetic Plast Surg. 2009;33(5):716-721.
 
Cervelli V, Gentile P. Use of cell fat mixed with platelet gel in progressive hemifacial atrophy. Aesthetic Plast Surg. 2009;33(1):22-27.
 
Cervelli V, Gentile P, Scioli MG, et al. Application of platelet-rich plasma in plastic surgery: clinical and in vitro evaluation. Tissue Eng Part C Methods. 2009; 15:1-9.
 
Sclafani AP. Platelet-rich fibrin matrix for improvement of deep nasolabial folds. J Cosmet Dermatol. 2010;9(1):66-71.
 
Sclafani AP. Applications of platelet-rich fibrin matrix in facial plastic surgery. Facial Plast Surg. 2009;25(4):270-276.
 
Sclafani AP. Safety, efficacy, and utility of platelet-rich fibrin matrix in facial plastic surgery [published online February 21, 2011]. Arch Facial Plast Surg. 2011;13(4):247-251.
 
Kakudo N, Minakata T, Mitsui T, Kushida S, Notodihardjo FZ, Kusumoto K.Proliferation-promoting effect of platelet-rich plasma on human adiposederived stem cells and human dermal fibroblasts. Plast Reconstr Surg. 2008; 122(5):1352-1360.
 
Oh DS, Cheon YW, Jeon YR, Lew DH. Activated platelet-rich plasma improves fat graft survival in nude mice: a pilot study. Dermatol Surg. 2011;37(5):619-625.
 
Anthony P. Sclafani, MD; Steven A. McCormick, MD. Induction of Dermal Collagenesis, Angiogenesis,and Adipogenesis in Human Skin by Injection of Platelet-Rich Fibrin Matrix. Arch Facial Plast Surg.Published online October 17, 2011. [Biopsy-proven new blood vessel growth and new collegen using platelet-derived growth factors (using a single-spin centrifuge)]
 
Gafni-Kane, Adam MD; Sand, Peter K. MD. Foreign-Body Granuloma After Injection of Calcium Hydroxylapatite for Type III Stress Urinary Incontinence. Obstetrics & Gynecology: August 2011 - Volume 118 - Issue 2, Part 2 - pp 418-421doi:10.1097/AOG.0b013e3182161953 [showed a significant incidence of granuloma formation after injectin Radiesse like materials to treat urinary incontinence. Conclusion is that benefit is worth the risk].
 
Alijotas-Reig, Jaume MD, PhD. Foreign-Body Granuloma After Injection of Calcium Hydroxylapatite for Treating Urinary Incontinence. Obstetrics & Gynecology: November 2011-Volume 118- Issue 5-p 1181-1182 doi: 10.1097/AOG.0b-12e318235962d [Letter to editor challenging the idea that the benefit is worth the risk when using Radiesse like materials to treat stress incontinence--the point is that even with a risk of complications that require surgery, some gynecologist consider injecting around the urethera with Radiesse or Juvederm like material (i.e. the G-Shot™) to be an accepted practice. Yet with the PRP used in the O-Shot™ there seems to be ZERO risk of granuloma with even more benefit]
 
The American College of Obstetricians and Gynecologists,Practice_Bulletin_No__119__Female_Sexual.38